The biggest difference is not being able to play your long
irons from the fairways, as ogallalabob said. If you are just out practicing, tee off on all the par 4's with your SW. From there, see if you can get on the green in two with your long
irons.
The fact that you are required to play course management and you are comfortable with that, puts you ahead of most golfers who are just aiming for the green with no consideration for the dangers that lie ahead.